Signaling pathway

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P504S rabbit pAb

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Article Number: PD0329
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: AMACR
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 42 kDa
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:1000-2000; ELISA 1:5000-20000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of Human,Mouse,Rat P504S
Gene name : AMACR
Protein Name : P504S
Alias : Alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase;

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011],

Cell localization : Peroxisome . Mitochondrion .

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