Signaling pathway

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DNM3A Polyclonal Antibody

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Article Number: PG8542
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: DNM3A
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 100 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : DNM3A Polyclonal Antibody detects endogenous levels of protein.
Gene name : DNMT3A
Protein Name : DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA)

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016],

Cell localization : Nucleus . Chromosome . Cytoplasm . Accumulates in the major satellite repeats at pericentric heterochromatin. .

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