Signaling pathway

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Jagged1 Polyclonal Antibody

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Article Number: PD2597
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Jagged1
Application: IF, WB, IHC, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 140 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IF 1:50-200;WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;Not yet tested in other applications;
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Jagged1 Polyclonal Antibody detects endogenous levels of Jagged1 protein.
Gene name : JAG1
Protein Name : Protein jagged-1
Alias : JAG1;JAGL1;Protein jagged-1;Jagged1;hJ1;CD339

Database connection:

Organism

Gene ID

SwissProt

Background:

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008],

Cell localization : Membrane; Single-pass type I membrane protein.

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