Signaling pathway

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CD248 Polyclonal Antibody

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Article Number: PD2706
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: CD248
Application: WB, ELISA
Reactivity : Human,Mouse
MW(Observed) : 80 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : CD248 Polyclonal Antibody detects endogenous levels of CD248 protein.
Gene name : CD248
Protein Name : Endosialin
Alias : CD248;CD164L1;TEM1;Endosialin;Tumor endothelial marker 1;CD248

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

function:May play a role in tumor angiogenesis.,online information:Endosialin,PTM:May be N-glycosylated.,PTM:O-glycosylated with sialylated oligosaccharides.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,tissue specificity:Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.,

Cell localization : Membrane ; Single-pass type I membrane protein .

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