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Signaling pathway
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Article Number: PD2801
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Target: BRMS-1
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 28 kD
Host Species: Rabbit
Isotype : IgG
隐藏域元素占位
Detailed Information
Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal
Antigen & Target Information
Specificity : BRMS-1 Polyclonal Antibody detects endogenous levels of BRMS-1 protein.
Gene name : BRMS1
Protein Name : Breast cancer metastasis-suppressor 1
Alias : BRMS1;Breast cancer metastasis-suppressor 1
Database connection:
Background:
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],


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