Signaling pathway

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TSG-6 Polyclonal Antibody

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Article Number: PD3161
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: TSG-6
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse
MW(Observed) : 31 kDa
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : TSG-6 Polyclonal Antibody detects endogenous levels of TSG-6 protein.
Gene name : TNFAIP6
Protein Name : Tumor necrosis factor-inducible gene 6 protein
Alias : TNFAIP6;TSG6;Tumor necrosis factor-inducible gene 6 protein;Hyaluronate-binding protein;TNF-stimulated gene 6 protein;TSG-6;Tumor necrosis factor alpha-induced protein 6;TNF alpha-induced protein 6

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.[provided by RefSeq, Dec 2010],

Cell localization : Secreted .

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