Signaling pathway

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TIN2 Polyclonal Antibody

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Article Number: PD3256
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: TIN2
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse
MW(Observed) : 53 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : TIN2 Polyclonal Antibody detects endogenous levels of TIN2 protein.
Gene name : TINF2
Protein Name : TERF1-interacting nuclear factor 2
Alias : TINF2;TIN2;TERF1-interacting nuclear factor 2;TRF1-interacting nuclear protein 2

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010],

Cell localization : Nucleus . Chromosome, telomere . Associated with telomeres.; [Isoform 1]: Nucleus matrix .

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