Signaling pathway

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TIMAP Polyclonal Antibody

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Article Number: PD3261
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: TIMAP
Application: WB, IHC
Reactivity : Human,Mouse
MW(Observed) : 64 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000;IHC 1:50-300
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : TIMAP Polyclonal Antibody detects endogenous levels of TIMAP protein.
Gene name : PPP1R16B
Protein Name : Protein phosphatase 1 regulatory inhibitor subunit 16B
Alias : PPP1R16B;ANKRD4;KIAA0823;Protein phosphatase 1 regulatory inhibitor subunit 16B;Ankyrin repeat domain-containing protein 4;CAAX box protein TIMAP;TGF-beta-inhibited membrane-associated protein;hTIMAP

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015],

Cell localization : Cell membrane . Cell membrane ; Lipid-anchor . Nucleus . Cell projection . Colocalizes with RPSA/LAMR1 in the cell membrane (PubMed:16263087). Localizes to the perinuclear region (By similarity). Colocalizes with PTEN at the tip of EC projections (PubMed:25007873). .

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