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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PD3866
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target： Rabaptin-5α
Application： IHC, IF, ELISA
Reactivity ： Human,Mouse,Rat
MW(CalcμLated) ： 99kD
Host Species： Rabbit
Isotype ： IgG
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： IHC 1:100-1:300; ELISA 1:40,000; IF 1:50-200
Compose ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Concentration ： 1 mg/ml
Clonality ： Polyclonal
Antigen & Target Information
Specificity ： Rabaptin-5α Polyclonal Antibody detects endogenous levels of Rabaptin-5α protein.
Gene name ： RABEP1
Protein Name ： Rab GTPase-binding effector protein 1
Alias ： RABEP1;RAB5EP;RABPT5;RABPT5A;Rab GTPase-binding effector protein 1;Rabaptin-4;Rabaptin-5;Rabaptin-5alpha;Renal carcinoma antigen NY-REN-17
Database connection:
Background：
function: Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.,PTM:Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity.,similarity:Belongs to the rabaptin family.,subunit:Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2.,
Cell localization ： Cytoplasm. Early endosome. Recycling endosome. Cytoplasmic vesicle.
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Wuhan Pinofibio Biotechnology Co., Ltd.
Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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