Signaling pathway

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PTH/PTHrP-R Polyclonal Antibody

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Article Number: PD3911
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: PTH/PTHrP-R
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 52 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : PTH/PTHrP-R Polyclonal Antibody detects endogenous levels of PTH/PTHrP-R protein.
Gene name : PTH1R
Protein Name : Parathyroid hormone/parathyroid hormone-related peptide receptor
Alias : PTH1R;PTHR;PTHR1;Parathyroid hormone/parathyroid hormone-related peptide receptor;PTH/PTHrP type I receptor;PTH/PTHr receptor;Parathyroid hormone 1 receptor;PTH1 receptor

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010],

Cell localization : Cell membrane ; Multi-pass membrane protein .

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