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PNPase Polyclonal Antibody

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Article Number: PD3992
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: PNPase
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse
MW(Observed) : 85 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : PNPase Polyclonal Antibody detects endogenous levels of PNPase protein.
Gene name : PNPT1
Protein Name : Polyribonucleotide nucleotidyltransferase 1 mitochondrial
Alias : PNPT1;PNPASE;Polyribonucleotide nucleotidyltransferase 1;mitochondrial;3'-5' RNA exonuclease OLD35;PNPase old-35;Polynucleotide phosphorylase 1;PNPase 1;Polynucleotide phosphorylase-like protein

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene belongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. This enzyme is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7. [provided by RefSeq, Dec 2012],

Cell localization : Cytoplasm . Mitochondrion matrix . Mitochondrion intermembrane space ; Peripheral membrane protein .

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