Signaling pathway

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Plakophilin 2 Polyclonal Antibody

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Article Number: PD4011
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Plakophilin 2
Application: WB, ELISA, IHC
Reactivity : Human, Rat
MW(Observed) : 97 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Plakophilin 2 Polyclonal Antibody detects endogenous levels of Plakophilin 2 protein.
Gene name : PKP2
Protein Name : Plakophilin-2
Alias : PKP2; Plakophilin-2

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008],

Cell localization : Nucleus . Cell junction, desmosome . Nuclear and associated with desmosomes.

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