Signaling pathway

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PDZK3 Polyclonal Antibody

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Article Number: PD4123
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: PDZK3
Application: IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 302 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : PDZK3 Polyclonal Antibody detects endogenous levels of PDZK3 protein.
Gene name : PDZD2
Protein Name : PDZ domain-containing protein 2
Alias : PDZD2;AIPC;KIAA0300;PDZK3;PDZ domain-containing protein 2;Activated in prostate cancer protein;PDZ domain-containing protein 3;[Cleaved into: Processed PDZ domain-containing protein 2]

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Dec 2015],

Cell localization : Nucleus . Cytoplasm . Endoplasmic reticulum . At cell-cell contacts in lung epithelial cells. .; [Processed PDZ domain-containing protein 2]: Secreted .

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