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NEIL3 Polyclonal Antibody

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Article Number: PD4632
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: NEIL3
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse
MW(Observed) : 68 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : NEIL3 Polyclonal Antibody detects endogenous levels of NEIL3 protein.
Gene name : NEIL3
Protein Name : Endonuclease 8-like 3
Alias : NEIL3; Endonuclease 8-like 3; DNA glycosylase FPG2; DNA glycosylase/AP lyase NEIL3; Endonuclease VIII-like 3; Nei-like protein 3

Database connection:

Organism

Gene ID

SwissProt

Background:

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008],

Cell localization : Nucleus . Chromosome . Recruited to replication stress sites via interaction with ubiquitinated CMG helicase. .

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