Signaling pathway

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NACAD Polyclonal Antibody

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Article Number: PD4686
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: NACAD
Application: WB, IHC
Reactivity : Human,Mouse
MW(Observed) : 140 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000;IHC 1:50-300
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : NACAD Polyclonal Antibody detects endogenous levels of NACAD protein.
Gene name : NACAD
Protein Name : NAC-alpha domain-containing protein 1
Alias : NACAD;KIAA0363;NAC-alpha domain-containing protein 1

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

function:May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).,similarity:Belongs to the NAC-alpha family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain.,

Cell localization : Cytoplasm . Nucleus .

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