Signaling pathway

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MMP-11 Polyclonal Antibody

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Article Number: PD4842
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: MMP-11
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 60 kDa
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : MMP-11 Polyclonal Antibody detects endogenous levels of MMP-11 protein.
Gene name : MMP11
Protein Name : Stromelysin-3
Alias : MMP11;STMY3;Stromelysin-3;SL-3;ST3;Matrix metalloproteinase-11;MMP-11

Database connection:

Organism

Gene ID

SwissProt

Background:

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008],

Cell localization : Secreted, extracellular space, extracellular matrix .

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