Signaling pathway

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MLK4 Polyclonal Antibody

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Article Number: PD4848
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: MLK4
Application: WB, ELISA, IHC
Reactivity : Human,Mouse
MW(Observed) : 110 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : MLK4 Polyclonal Antibody detects endogenous levels of MLK4 protein.
Gene name : MLK4
Protein Name : Mitogen-activated protein kinase kinase kinase MLK4
Alias : MLK4;KIAA1804;Mitogen-activated protein kinase kinase kinase MLK4;Mixed lineage kinase 4

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation.,function:Activates the JUN N-terminal pathway.,PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH3 domain.,subunit:Homodimer.,

Cell localization : intracellular,

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