Signaling pathway

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KIF2C Polyclonal Antibody

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Article Number: PD5120
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: KIF2C
Application: WB, ELISA, IHC
Reactivity : Human,Mouse
MW(CalcμLated) : 81kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : KIF2C Polyclonal Antibody detects endogenous levels of KIF2C protein.
Gene name : KIF2C
Protein Name : Kinesin-like protein KIF2C
Alias : KIF2C;KNSL6;Kinesin-like protein KIF2C;Kinesin-like protein 6;Mitotic centromere-associated kinesin;MCAK

Database connection:

Organism

Gene ID

SwissProt

Background:

kinesin family member 2C(KIF2C) Homo sapiens This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

Cell localization : Cytoplasm, cytoskeleton . Nucleus . Chromosome, centromere . Chromosome, centromere, kinetochore . Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1 (By similarity). Association with microtubule plus ends is also mediated by interaction with KIF18B. Centromeric localization requires the presence of BUB1 and SGO2. .

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