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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PD5319
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target： hnRNP L
Application： WB, IHC, IF, ELISA
Reactivity ： Human,Mouse
MW(Observed) ： 60 kDa
Host Species： Rabbit
Isotype ： IgG
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Compose ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Concentration ： 1 mg/ml
Clonality ： Polyclonal
Antigen & Target Information
Specificity ： hnRNP L Polyclonal Antibody detects endogenous levels of hnRNP L protein.
Gene name ： HNRNPL
Protein Name ： Heterogeneous nuclear ribonucleoprotein L
Alias ： HNRNPL;HNRPL;P/OKcl.14;Heterogeneous nuclear ribonucleoprotein L;hnRNP L
Background：
Heterogeneous nuclear RNAs (hnRNAs), which include mRNA precursors and mature mRNAs, associate with specific proteins to form heterogeneous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is one of the proteins that stably associates with hnRNP complexes and, together with other hnRNP proteins, likely plays a crucial role in the assembly, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside the nucleoplasm. The exchange of hnRNP components for mRNA-binding proteins accompanies the transport of mRNA from the nucleus to the cytoplasm. Given that HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is plausible that they may also perform functions in the cytoplasm. Two transcript variants encoding different isoforms…
Cell localization ： Nucleus, nucleoplasm . Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. These granules are not identical with P bodies or stress granules. .
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Wuhan Pinofibio Biotechnology Co., Ltd.
Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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