Signaling pathway

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GUF1 Polyclonal Antibody

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Article Number: PD5409
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: GUF1
Application: IHC, IF, ELISA
Reactivity : Human,Mouse
MW(CalcμLated) : 74 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : GUF1 Polyclonal Antibody detects endogenous levels of GUF1 protein.
Gene name : GUF1
Protein Name : Translation factor GUF1 mitochondrial
Alias : GUF1;Translation factor GUF1;mitochondrial;Elongation factor 4 homolog;EF-4;GTPase GUF1;Ribosomal back-translocase

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],

Cell localization : Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .

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