Signaling pathway

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GROα Polyclonal Antibody

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Article Number: PD5422
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Detailed Information

Recommended dilution ratio : IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : GROα Polyclonal Antibody detects endogenous levels of GROα protein.
Gene name : CXCL1
Protein Name : Growth-regulated alpha protein
Alias : CXCL1;GRO;GRO1;GROA;MGSA;SCYB1;Growth-regulated alpha protein;C-X-C motif chemokine 1;GRO-alpha;1-73;Melanoma growth stimulatory activity;MGSA;Neutrophil-activating protein 3;NAP-3

Database connection:

Organism

Gene ID

SwissProt

Background:

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014],

Cell localization : Secreted.

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