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Article Number: PD5716
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Target: Fnk
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 70 kD
Host Species: Rabbit
Isotype : IgG
隐藏域元素占位
Detailed Information
Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal
Antigen & Target Information
Specificity : Fnk Polyclonal Antibody detects endogenous levels of Fnk protein.
Gene name : PLK3
Protein Name : Serine/threonine-protein kinase PLK3
Alias : PLK3;CNK;FNK;PRK;Serine/threonine-protein kinase PLK3;Cytokine-inducible serine/threonine-protein kinase;FGF-inducible kinase;Polo-like kinase 3;PLK-3;Proliferation-related kinase
Background:
The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis. [provided by RefSeq, Sep 2015],


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