Signaling pathway

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EphB4 Polyclonal Antibody

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Article Number: PD5829
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: EphB4
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse
MW(Observed) : 108 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : EphB4 Polyclonal Antibody detects endogenous levels of EphB4 protein.
Gene name : EPHB4
Protein Name : Ephrin type-B receptor 4
Alias : EPHB4;HTK;MYK1;TYRO11;Ephrin type-B receptor 4;Hepatoma transmembrane kinase;Tyrosine-protein kinase TYRO11

Database connection:

Organism

Gene ID

SwissProt

Background:

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008],

Cell localization : Cell membrane ; Single-pass type I membrane protein .

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