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Epac Polyclonal Antibody

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Article Number: PD5845
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Epac
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 100 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Epac Polyclonal Antibody detects endogenous levels of Epac protein.
Gene name : RAPGEF3
Protein Name : Rap guanine nucleotide exchange factor 3
Alias : RAPGEF3;CGEF1;EPAC;EPAC1;Rap guanine nucleotide exchange factor 3;Exchange factor directly activated by cAMP 1;Exchange protein directly activated by cAMP 1;EPAC 1;Rap1 guanine-nucleotide-exchange factor directly activated by cAMP;

Database connection:

Organism

Gene ID

SwissProt

Background:

caution:It is uncertain whether Met-1 or Met-43 is the initiator.,domain:The DEP domain is involved in membrane localization independent from regulation by cAMP.,function:Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP.,similarity:Contains 1 cyclic nucleotide-binding domain.,similarity:Contains 1 DEP domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-GEF domain.,tissue specificity:Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney.,

Cell localization : Endomembrane system .

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