Signaling pathway

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DGK-θ Polyclonal Antibody

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Article Number: PD6042
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: DGK-θ
Application: WB, IHC, IF, ELISA
Reactivity : Human, Rat, Mouse,
MW(Observed) : 101 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : DGK-θ Polyclonal Antibody detects endogenous levels of DGK-θ protein.
Gene name : DGKQ
Protein Name : Diacylglycerol kinase theta
Alias : DGKQ;DAGK4;Diacylglycerol kinase theta;DAG kinase theta;Diglyceride kinase theta;DGK-theta

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

The protein encoded by this gene contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasm . Cytoplasm, cytosol . Cell membrane . Cell junction, synapse . Cytoplasm, cytoskeleton . Nucleus . Nucleus speckle . Nucleus matrix . Translocates to the plasma membrane in response to steroid hormone receptor stimulation (PubMed:15632189). Translocation to the plasma membrane is dependent on G-protein coupled receptor stimulation and subsequent activation of PRKCE and probably PRKCH (PubMed:15632189). Translocates to the nucleus in response to thrombin stimulation (Probable). Association with the nuclear matrix is regulated by nerve growth factor (By similarity). .

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