Signaling pathway

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CYP1A2 Polyclonal Antibody

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Article Number: PD6174
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: CYP1A2
Application: IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 58 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : CYP1A2 Polyclonal Antibody detects endogenous levels of CYP1A2 protein.
Gene name : CYP1A2
Protein Name : Cytochrome P450 1A2
Alias : CYP1A2;Cytochrome P450 1A2;CYPIA2;Cytochrome P;3;450;Cytochrome P450 4;Cytochrome P450-P3

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008],

Cell localization : Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane ; Peripheral membrane protein.

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