Signaling pathway

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Connexin 47 Polyclonal Antibody

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Article Number: PD6294
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Connexin 47
Application: WB, IF, ELISA
Reactivity : Human, Rat, Mouse,
MW(Observed) : 47 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Connexin 47 Polyclonal Antibody detects endogenous levels of Connexin 47 protein.
Gene name : GJC2
Protein Name : Gap junction gamma-2 protein
Alias : GJC2;GJA12;Gap junction gamma-2 protein;Connexin-46.6;Cx46.6;Connexin-47;Cx47;Gap junction alpha-12 protein

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1. [provided by RefSeq, Jul 2008],

Cell localization : Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

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