Signaling pathway

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Cdc42EP5 Polyclonal Antibody

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Article Number: PD6499
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Cdc42EP5
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse
MW(Observed) : 22 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Cdc42EP5 Polyclonal Antibody detects endogenous levels of Cdc42EP5 protein.
Gene name : CDC42EP5
Protein Name : Cdc42 effector protein 5
Alias : CDC42EP5;BORG3;CEP5;Cdc42 effector protein 5;Binder of Rho GTPases 3

Database connection:

Organism

Gene ID

SwissProt

Background:

Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013],

Cell localization : Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton .

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