Signaling pathway

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Bradykinin B1 R Polyclonal Antibody

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Article Number: PD6744
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Bradykinin B1 R
Application: WB, IF, ELISA
Reactivity : Human, Rat, Mouse,
MW(Observed) : 40 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Bradykinin B1 R Polyclonal Antibody detects endogenous levels of Bradykinin B1 R protein.
Gene name : BDKRB1
Protein Name : B1 bradykinin receptor
Alias : BDKRB1;BRADYB1;B1 bradykinin receptor;B1R;BK-1 receptor

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

Cell localization : Cell membrane; Multi-pass membrane protein.

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