Signaling pathway

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AR-β1 Polyclonal Antibody

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Article Number: PD6882
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: AR-β1
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 51 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : AR-β1 Polyclonal Antibody detects endogenous levels of AR-β1 protein.
Gene name : ADRB1
Protein Name : Beta-1 adrenergic receptor
Alias : ADRB1;ADRB1R;B1AR;Beta-1 adrenergic receptor;Beta-1 adrenoreceptor;Beta-1 adrenoceptor

Database connection:

Organism

Gene ID

SwissProt

Background:

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008],

Cell localization : Cell membrane; Multi-pass membrane protein. Early endosome. Colocalizes with RAPGEF2 at the plasma membrane (By similarity). Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression. .

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