Signaling pathway

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ARHGAP11A Polyclonal Antibody

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Article Number: PD6925
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: ARHGAP11A
Application: WB, ELISA
Reactivity : Human,Mouse
MW(Observed) : 110 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : ARHGAP11A Polyclonal Antibody detects endogenous levels of ARHGAP11A protein.
Gene name : ARHGAP11A
Protein Name : Rho GTPase-activating protein 11A
Alias : ARHGAP11A;KIAA0013;Rho GTPase-activating protein 11A;Rho-type GTPase-activating protein 11A

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. [provided by RefSeq, Sep 2016],

Cell localization : Nucleus .

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