Signaling pathway

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Actinin-α3 Polyclonal Antibody

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Article Number: PD7103
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Actinin-α3
Application: WB, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 103 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Actinin-α3 Polyclonal Antibody detects endogenous levels of Actinin-α3 protein.
Gene name : ACTN3
Protein Name : Alpha-actinin-3
Alias : ACTN3;Alpha-actinin-3;Alpha-actinin skeletal muscle isoform 3;F-actin cross-linking protein

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status. [provided by RefSeq, Feb 2014],

Cell localization : intracellular, cytosol, actin filament, brush border, focal adhesion, Z disc, pseudopodium, extracellular exosome,

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