Signaling pathway

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JAK3 (Phospho Tyr904) rabbit pAb

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Article Number: PF0207
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: JAK3
Application: World Bank
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 124 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Modify-Modification : Phospho
Recommended dilution ratio : WB 1:500-2000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of JAK3 (Phospho-Tyr904) at Human, Mouse,Rat
Gene name : JAK3
Protein Name : JAK3 (Phospho-Tyr904)
Alias : Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK;

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],

Cell localization : Endomembrane system ; Peripheral membrane protein . Cytoplasm .

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