Signaling pathway

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APC1 (phospho Ser688) Polyclonal Antibody

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Article Number: PF0768
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: APC1
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 217 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Modify-Modification : Phospho
Recommended dilution ratio : WB 1:500-2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Phospho-APC1 (S688) Polyclonal Antibody detects endogenous levels of APC1 protein only when phosphorylated at S688.
Gene name : ANAPC1
Protein Name : Anaphase-promoting complex subunit 1
Alias : ANAPC1;TSG24;Anaphase-promoting complex subunit 1;APC1;Cyclosome subunit 1;Mitotic checkpoint regulator;Testis-specific gene 24 protein

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011],

Cell localization : nucleoplasm, anaphase-promoting complex, cytosol,

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