Signaling pathway

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STAM2 (phospho Tyr192) Polyclonal Antibody

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Article Number: PF1517
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: STAM2
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse
MW(Observed) : 58 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Modify-Modification : Phospho
Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Phospho-STAM2 (Y192) Polyclonal Antibody detects endogenous levels of STAM2 protein only when phosphorylated at Y192.
Gene name : STAM2
Protein Name : Signal transducing adapter molecule 2
Alias : STAM2;HBP;Signal transducing adapter molecule 2;STAM-2;Hrs-binding protein

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasm . Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .

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