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Article Number: PF1566
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target: CD50/ICAM-3
Application: WB, ELISA
Reactivity : Human
MW(Observed) : 42-60 kDa
Host Species: Rabbit
Isotype : IgG
隐藏域元素占位
Detailed Information
Modify-Modification : Phospho
Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal
Antigen & Target Information
Specificity : Phospho-CD50 (S518) Polyclonal Antibody detects endogenous levels of CD50 protein only when phosphorylated at S518.
Gene name : ICAM3
Protein Name : Intercellular adhesion molecule 3
Alias : ICAM3; Intercellular adhesion molecule 3; ICAM-3; CDw50; ICAM-R; CD antigen CD50
Background:
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],


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