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Article Number: PF1864
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target: CD3 zeta
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat,Monkey
MW(Observed) : 20 kD
Host Species: Rabbit
Isotype : IgG
隐藏域元素占位
Detailed Information
Modify-Modification : Phospho
Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal
Antigen & Target Information
Specificity : Phospho-CD3 ζ (Y142) Polyclonal Antibody detects endogenous levels of CD3 ζ protein only when phosphorylated at Y142.
Gene name : CD247
Protein Name : T-cell surface glycoprotein CD3 zeta chain
Alias : CD247;CD3Z;T3Z;TCRZ;T-cell surface glycoprotein CD3 zeta chain;T-cell receptor T3 zeta chain;CD antigen CD247
Background:
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],


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