Signaling pathway

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Cleaved-ITI-H1 (D672) Polyclonal Antibody

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Article Number: PK0220
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: ITI-H1
Application: WB, ELISA
Reactivity : Human,Mouse
MW(Observed) : 71 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Cleaved-ITI-H1 (D672) Polyclonal Antibody detects endogenous levels of fragment of activated ITI-H1 protein resulting from cleavage adjacent to D672.
Gene name : ITIH1
Protein Name : Inter-alpha-trypsin inhibitor heavy chain H1
Alias : ITIH1;IGHEP1;Inter-alpha-trypsin inhibitor heavy chain H1;ITI heavy chain H1;ITI-HC1;Inter-alpha-inhibitor heavy chain 1;Inter-alpha-trypsin inhibitor complex component III;Serum-derived hyaluronan-associated protein;SHAP

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a member of the inter-alpha-trypsin inhibitor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter-alpha-trypsin inhibitor complex, which is secreted by hepatocytes into the blood. The heavy chain also interacts with hyaluronan, and this interaction may play a role in ovulation and fertilization, and has been implicated in multiple inflammatory diseases. This gene is present in a gene cluster on chromosome 3. [provided by RefSeq, Nov 2015],

Cell localization : Secreted.

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