Signaling pathway

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Cleaved-PAR-4 (G48) Polyclonal Antibody

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Article Number: PK0241
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: PAR-4
Application: WB, ELISA
Reactivity : Human, Rat, Mouse,
MW(Observed) : 33 kDa
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Cleaved-PAR-4 (G48) Polyclonal Antibody detects endogenous levels of fragment of activated PAR-4 protein resulting from cleavage adjacent to G48.
Gene name : F2RL3
Protein Name : Proteinase-activated receptor 4
Alias : F2RL3;PAR4;Proteinase-activated receptor 4;PAR-4;Coagulation factor II receptor-like 3;Thrombin receptor-like 3

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016],

Cell localization : Cell membrane; Multi-pass membrane protein.

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