Signaling pathway

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Cleaved-KLK11 (I54) Polyclonal Antibody

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Article Number: PK0258
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: KLK11
Application: WB, ELISA
Reactivity : Human, Rat, Mouse,
MW(Observed) : 25 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Cleaved-KLK11 (I54) Polyclonal Antibody detects endogenous levels of fragment of activated KLK11 protein resulting from cleavage adjacent to I54.
Gene name : KLK11
Protein Name : Kallikrein-11
Alias : KLK11;PRSS20;TLSP;Kallikrein-11;hK11;Hippostasin;Serine protease 20;Trypsin-like protease

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.[provided by RefSeq, Nov 2009],

Cell localization : [Isoform 1]: Secreted.; [Isoform 2]: Golgi apparatus.

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