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KSP-Cadherin (PT0160) mouse mAb

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Article Number: PH0252
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: KSP-Cadherin
Application: IHC, ELISA
Reactivity : Human,
MW(CalcμLated) : 90 kD
Host Species: Mouse
Isotype : IgG1, Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-400; ELISA 1:500-5000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0160

Antigen & Target Information

Specificity : The antibody can specifically recognize human KSP-Cadherin protein, and has no cross reaction with E-cadherin, N-cadherin, P-cadherin.
Gene name : CDH16 UNQ695/PRO1340
Protein Name : KSP-Cadherin
Alias : CDH16;Cadherin-16;Kidney-specific cadherin;Ksp-cadherin

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011],

Cell localization : Cytoplasmic, Membranous

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