Signaling pathway

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Cytokeratin 13 (ABT057) mouse mAb

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Article Number: PH0311
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Cytokeratin 13
Application: IHC, ELISA
Reactivity : Human,
MW(CalcμLated) : 50 kD
MW(Observed) : 50 kD
Host Species: Mouse
Isotype : IgG1, Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-400; ELISA 1:500-5000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : ABT057

Antigen & Target Information

Specificity : The antibody can specifically recognize human CK13 protein.
Gene name : KRT13
Protein Name : 47 kDa cytokeratin;CK-13;CK13;Cytokeratin 13;Cytokeratin-13;K13;K1C13_HUMAN;Ka13;Keratin 13;Keratin;keratin type I cytoskeletal 13;Keratin-13;Krt-1.13;Krt1-13;KRT13;MGC161462;MGC3781;type I cytoskeletal 13;Type I keratin Ka13;WSN2
Alias : 47 kDa cytokeratin;CK-13;CK13;Cytokeratin 13;Cytokeratin-13;K13;K1C13_HUMAN;Ka13;Keratin 13;Keratin;keratin type I cytoskeletal 13;Keratin-13;Krt-1.13;Krt1-13;KRT13;MGC161462;MGC3781;type I cytoskeletal 13;Type I keratin Ka13;WSN2

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasmic, Membranous

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