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Article Number: PL0391
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target: K-Ras
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 22 kD
MW(Observed) : 22 kD
Host Species: Rabbit
Isotype : IgG, Kappa
隐藏域元素占位
Detailed Information
Recommended dilution ratio : IHC 1:100-1:500; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clone Number : Monoclonal
Antigen & Target Information
Specificity : Endogenous
Gene name : KRAS
Protein Name : v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Alias : GTPase KRas;K-Ras 2;Ki-Ras;c-K-ras;c-Ki-ras;
Background:
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008],


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