Signaling pathway

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K-Ras Rabbit mAb

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Article Number: PL0391
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: K-Ras
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 22 kD
MW(Observed) : 22 kD
Host Species: Rabbit
Isotype : IgG, Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:100-1:500; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clone Number : Monoclonal

Antigen & Target Information

Specificity : Endogenous
Gene name : KRAS
Protein Name : v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Alias : GTPase KRas;K-Ras 2;Ki-Ras;c-K-ras;c-Ki-ras;

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008],

Cell localization : Cell membrane ; Lipid-anchor ; Cytoplasmic side . Endomembrane system . Cytoplasm, cytosol .; [Isoform 2B]: Cell membrane ; Lipid-anchor .

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