Signaling pathway

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Snail Rabbit mAb

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Article Number: PL0807
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: SNAI1
Application: WB, IF, IP, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 29 kDa
MW(Observed) : 29 kDa
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clone Number : PT0718R

Antigen & Target Information

Specificity : Endogenous
Gene name : SNAI1
Protein Name : Zinc finger protein SNAI1(snail)
Alias : SNAI1;SNAH;Zinc finger protein SNAI1;Protein snail homolog 1;Protein sna

Database connection:

Organism

Gene ID

SwissProt

Background:

snail family transcriptional repressor 1(SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008],

Cell localization : Nucleus . Cytoplasm . Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. .

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