Signaling pathway

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Synapsin I Rabbit mAb

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Article Number: PL1137
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Synapsin I
Application: WB, IHC, IF, IP, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 74 kD
MW(Observed) : 74.70 kD
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0602R

Antigen & Target Information

Specificity : Endogenous
Gene name : SYN1
Protein Name : Synapsin-1
Alias : SYN1;Synapsin-1;Brain protein 4.1;Synapsin I

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Cell localization : Synapse

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