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Article Number: PL1260
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target: ACSL4
Application: WB, IHC, IF, IP, ELISA
Reactivity : Human,Mouse,Rat,
MW(CalcμLated) : 78 kD
MW(Observed) : 78 kD
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified
隐藏域元素占位
Detailed Information
Recommended dilution ratio : IHC 1:200-1:2000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0448R
Antigen & Target Information
Specificity : Endogenous
Gene name : ACSL4 ACS4 FACL4 LACS4
Protein Name : ACSL4
Alias : Long-chain-fatty-acid--CoA ligase 4; Long-chain acyl-CoA synthetase 4; LACS 4;
Database connection:
Background:
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the cognitive disability or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jan 2016]


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