Signaling pathway

Contact Us

15392937510

Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510

Image Name

Notch2 Rabbit mAb

Copy

Download
Article Number: PL1328
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
undefined
+
  • undefined


Target: Notch 2
Application: WB, IHC, IF, IP, ELISA
Reactivity : Human,Mouse,Rat,
MW(CalcμLated) : 265 kD
MW(Observed) : 120 kD
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:100-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0367R

Antigen & Target Information

Specificity : Endogenous
Gene name : NOTCH2
Protein Name : Neurogenic locus notch homolog protein 2
Alias : NOTCH2;Neurogenic locus notch homolog protein 2;Notch 2;hN2

Database connection:

Organism

Gene ID

SwissProt

Background:

notch 2(NOTCH2) Homo sapiens This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cle

Cell localization : Cytoplasm, Membrane

Recommended

Relevant Literature

Leave a message for inquiry

Please leave your inquiry, and we will contact you as soon as possible.

Submit