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Article Number: PL1328
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target: Notch 2
Application: WB, IHC, IF, IP, ELISA
Reactivity : Human,Mouse,Rat,
MW(CalcμLated) : 265 kD
MW(Observed) : 120 kD
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified
隐藏域元素占位
Detailed Information
Recommended dilution ratio : IHC 1:100-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0367R
Antigen & Target Information
Specificity : Endogenous
Gene name : NOTCH2
Protein Name : Neurogenic locus notch homolog protein 2
Alias : NOTCH2;Neurogenic locus notch homolog protein 2;Notch 2;hN2
Database connection:
Background:
notch 2(NOTCH2) Homo sapiens This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cle


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