Signaling pathway

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BMP2 Rabbit mAb

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Article Number: PL1332
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: BMP-2
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat,
MW(CalcμLated) : 45 kD, 13 kD
MW(Observed) : 30kD,13kD
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0362R

Antigen & Target Information

Specificity : Endogenous
Gene name : BMP2
Protein Name : Bone morphogenetic protein 2
Alias : BMP2;BMP2A;Bone morphogenetic protein 2;BMP-2;Bone morphogenetic protein 2A;BMP-2A

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016],

Cell localization : Secreted

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