Signaling pathway

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Rab7 Rabbit mAb

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Article Number: PL1342
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: RAB7
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat,
MW(CalcμLated) : 24kD
MW(Observed) : 24kD
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0345R

Antigen & Target Information

Specificity : Endogenous
Gene name : RAB7A RAB7
Protein Name : RAB7A

Database connection:

Organism

Gene ID

SwissProt

Background:

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasm

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