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Signaling pathway
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Article Number: PL1363
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target: Rab 5A
Application: WB, IHC, IF, IP, ELISA
Reactivity : Human,Mouse,Rat,
MW(CalcμLated) : 24kD
MW(Observed) : 24kD
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified
隐藏域元素占位
Detailed Information
Recommended dilution ratio : IHC 1:1000-1:4000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200,
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0309R
Antigen & Target Information
Specificity : Endogenous
Gene name : >>Ras signaling pathway;>>Endocytosis;>>Phagosome;>>Vasopressin-regulated water reabsorption;>>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases;>>Salmonella infection;>>Amoebiasis;>>Tuberculosis
Protein Name : RAB5A
Alias : RAB5A;RAB5;Ras-related protein Rab-5A
Background:
enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,function:Required for the fusion of plasma membranes and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Enriched in stage I melanosomes.,subunit:Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, UNC84B, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3.,


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